Mer ydmykhet

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A Comparison of Human O6-Methylguanine-DNA Methyltransferase Promoter Activity in Mer+ and Mer~ Cells1

The activity of the human 06-methylguanine-DNA methyltransferase (MGMT) gene promoter was determined in eight human cell lines by measuring chloramphenicol acetyltransferase activity in a re porter gene system. MGMT promoter activities in cells that do not express MGMT (Mer ) fell within the range of activities seen in cells that do express MGMT (Mer4). The promoter region contains 11 po tentia...

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Modélisation du déroulement d'activités humaines en mer côtière. Scénarios appliqués à la mer d'Iroise

Coastal seas, marine part of the coastal zone, are particulary attractive for human society. Human activities involve interactions that can lead to conflicts and to ressources degradation. In order to analyse the coastal system, the Geomer laboratory has developed a modelling platform of Human Activities Dynamic (DAHU) which contains a specific module adapted to the human marine activities (DAH...

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A comparison of human O6-methylguanine-DNA methyltransferase promoter activity in Mer+ and Mer- cells.

The activity of the human O6-methylguanine-DNA methyltransferase (MGMT) gene promoter was determined in eight human cell lines by measuring chloramphenicol acetyltransferase activity in a reporter gene system. MGMT promoter activities in cells that do not express MGMT (Mer-) fell within the range of activities seen in cells that do express MGMT (Mer+). The promoter region contains 11 potential ...

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In vitro synergic antifungal effect of MUC7 12-mer with histatin-5 12-mer or miconazole.

OBJECTIVES MUC7 12-mer (RKSYKCLHKRCR), a cationic peptide derived from human salivary MUC7 mucin, exhibits potent in vitro antifungal activity, as determined by killing assays in phosphate buffer. In this study we examined the MUC7 12-mer antifungal activity alone or in combination with other antifungal agents in LYM medium (modified RPMI 1640). METHODS Antifungal activities of MUC7 12-mer an...

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Expression of the O6-methylguanine-DNA methyltransferase gene MGMT in MER+ and MER- human tumor cells.

DNA probes prepared from human O6-methylguanine-DNA methyltransferase complementary DNA were hybridized to mRNA isolated from human liver and fifteen human tumor cell lines proficient (Mer+) or deficient (Mer-) in transferase activity. Liver and Mer+ cells contained levels of transferase-specific mRNA that correlated with their transferase activity levels, whereas Mer- cells contained undetecta...

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ژورنال

عنوان ژورنال: Stat & Styring

سال: 2021

ISSN: 0809-750X,0803-0103

DOI: 10.18261/issn0809-750x-2021-01-01